The distant organ effects of acute kidney injury

Distant organ injury following acute kidney injury.

ACUTE KIDNEY INJURY (AKI) is associated with unacceptably high mortality that can range from 40 to 60% in some cases (14). The incidence of AKI continues to increase (15, 16) and is associated with a changing spectrum of illnesses, significant comorbid and extrarenal complications (12), and unsatisfactory preventive or treatment strategies (5). The etiology of AKI is diverse, and ischemia const...

Ischemic acute kidney injury induces a distant organ functional and genomic response distinguishable from bilateral nephrectomy.

Acute kidney injury (AKI) is associated with significant mortality, which increases further when combined with acute lung injury. Experiments in rodents have shown that kidney ischemia-reperfusion injury (IRI) facilitates lung injury and inflammation. To identify potential ischemia-specific lung molecular pathways involved, we conducted global gene expression profiling of lung 6 or 36 h followi...

the plain x-ray the diagnosis of the acute abdomen_

چکیده ندارد.

Inflammatory Mechanisms of Organ Crosstalk during Ischemic Acute Kidney Injury

Acute kidney injury (AKI) is a common complication during inpatient hospitalization, and clinical outcomes remain poor despite advancements in renal replacement therapy. AKI in the setting of multiple organ failure (MOF) remains a formidable challenge to clinicians and incurs an unacceptably high mortality rate. Kidney ischemia-reperfusion injury (IRI) incites a proinflammatory cascade and rele...

NGAL, the New Marker for Acute Kidney Injury